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Bone healthĪromatase inhibitors cause a loss of bone density, which leads to higher rates of osteoporosis and bone fractures compared to tamoxifen. Your health care provider may also switch you to another aromatase inhibitor (you may have less pain with a different drug) or recommend tamoxifen. Getting regular physical activity (such as walking, stretching or yoga) may reduce joint and muscle pain. Your health care provider may recommend anti-inflammatory medications (such as aspirin or ibuprofen), special exercises or acupuncture to ease the pain. If you have joint or muscle pain while taking an aromatase inhibitor, talk with your health care provider.
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Īlthough aromatase inhibitors can cause joint and muscle pain, they don’t cause permanent joint or muscle damage. In rare cases, aromatase inhibitors can cause carpal tunnel syndrome. Joint and muscle pain can mimic carpal tunnel syndrome. Joint and muscle pain are most common after you’ve been sleeping or inactive.Īlmost half of women taking aromatase inhibitors have joint pain and about 15 percent have muscle pain. The pain may be in the hands and wrists, feet and ankles, knees, back or other parts of the body. Joint pain (arthralgia) and muscle pain (myalgia) are common side effects of aromatase inhibitors. Some common side effects are described below. Premenopausal women who also get ovarian suppression.They include:Īromatase inhibitors are used to treat breast cancers in: Aromatase inhibitors are hormone therapy drugs used to treat hormone receptor-positive breast cancer.